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US 12,006,311 B2Granted
Compounds for use in preventing or treating cancer
AssigneesFundació Hospital Universitari Vall D'Hebroninstitut De Recerca, Institut Univ. De CièNcia I Tecnologia, S. A.
InventorsJosep Roma Castanyer, Marta Pascual Gilabert, José Sánchez De Toledo Codina, Soledad Gallego Melcón, Patricia Zarzosa Martínez, Javier Alonso Fernández, Sergio Pérez Ozcáriz, Cristina López Gómez, Josep Castells Boliart
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Abstract
The present invention relates to compounds of formula (I) for use in preventing and/or treating cancer.
Claims15
A compound selected from the group consisting of:
- 4,5-Dichloro-N-(1-(3-fluoro-2′-methoxy-[1,1′-biphenyl]-4-yl)-2-oxopiperidin-3-yl)thiophene-2-sulfonamide;
- N-(1-(3-fluoro-2′-methoxy-[1,1′-biphenyl]-4-yl)-2-oxopiperidin-3-yl)-3,5-dimethylisoxazole-4-sulfonamide;
- N-(1-(3-fluoro-2′-methoxy-[1,1′-biphenyl]-4-yl)-2-oxopiperidin-3-yl)benzo[d][1,3] dioxole-5-sulfonamide;
- N-(1-(3-fluoro-2′-methoxy-[1,1′-biphenyl]-4-yl)-2-oxopiperidin-3-yl)-5-(pyridin-2-yl)thiophene-2-sulfonamide;
- N-(1-(3-fluoro-2′-methoxy-[1,1′-biphenyl]-4-yl)-2-oxopiperidin-3-yl)benzofuran-2-sulfonamide;
- 4,5-Dichloro-N-(cyanomethyl)-N-(1-(3-fluoro-2′-methoxy-[1,1′-biphenyl]-4-yl)-2-oxopiperidin-3-yl)thiophene-2-sulfonamide;
- Ethyl N-(benzo[d][1,3]dioxol-5-ylsulfonyl)-N-(1-(3-fluoro-2′-methoxy-[1,1′-biphenyl]-4-yl)-2-oxopiperidin-3-yl)glycinate;
- N-(1-(3-fluoro-2′-methoxy-[1,1′-biphenyl]-4-yl)-2-oxopiperidin-3-yl)-N-(2-morpholino-2-oxoethyl)benzo[d][1,3]dioxole-5-sulfonamide;
- 2-((4,5-dichloro-N-(1-(3-fluoro-2′-methoxy-[1,1′-biphenyl]-4-yl)-2-oxopiperidin-3-yl)thiophene)-2-sulfonamido)acetamide;
- and
- Ethyl N-(1-(3-fluoro-2′-methoxy-[1,1′-biphenyl]-4-yl)-2-oxopiperidin-3-yl)-N-((5-(pyridin-2-yl)thiophen-2-yl)sulfonyl)glycinate;
- or a salt thereof.
9 more elements
Dependencies are inferred from the claim text.