Drug delivery systems including displaceable closures

A drug delivery system comprising:

• a drug containing device comprising:
• a first body comprising a chamber carrying a fluid drug, and an outlet in fluid communication with the chamber, the first body having an outer cross-sectional area;
• and
• a first closure detachably carried by the first body at the outlet and configured to inhibit the fluid drug from exiting the drug containing device via the outlet;
• and
• a drug delivery device comprising:
• a second body including a recess defined therein and a fluid passageway defined therein, the recess having an inner cross-sectional area sized similar to the outer cross-sectional area to allow for a snug fit when the recess receives the first body;
• a stem extending within the recess from the second body and defining an inlet, the stem configured to displace the first closure from the outlet and enter through the outlet, wherein the inlet is configured to fluidly interconnect the chamber and the fluid passageway and thereby facilitate delivery of the fluid drug from the drug containing device to the drug delivery device;
• a second closure associated with the stem, the second closure configured to engage the first body at the outlet when the stem enters the outlet to inhibit the fluid drug from exiting the drug containing device between the first body and the stem;
• and
• a drug delivery element in fluid communication with the fluid passageway.

A drug delivery system having an uncoupled configuration and a coupled configuration, the drug delivery system comprising:

• a drug containing device comprising:
• a first body comprising a chamber carrying a fluid drug and an outlet in fluid communication with the chamber;
• and
• a first closure detachably carried by the first body at the outlet;
• and
• a drug delivery device comprising:
• a second body comprising a fluid passageway;
• a stem coupled to the second body and comprising an inlet in fluid communication with the fluid passageway;
• a second closure coupled to the stem;
• and
• a drug delivery element in fluid communication with the fluid passageway;
• wherein:
• in the uncoupled configuration, the first closure is carried by the first body at the outlet to inhibit the fluid drug from exiting the drug containing device via the outlet;
• and
• in the coupled configuration, the first closure is displaced from the outlet by the stem, the second closure is engaged with the first body at the outlet, and the fluid drug is permitted to travel from the chamber to the fluid passageway via the inlet, for delivery to the drug delivery element.