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US 12,005,139 B2Granted
Ophthalmic formulations and related methods
AssigneeEternatear, Inc.
InventorsTimothy R Willis, Ralph P. Stone
Life of this patent
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Abstract
This disclosure is directed to ophthalmic suspensions for dry eye and other ocular indications that provide long-lasting on eye benefits. The disclosure provides methods of increasing lipid layer thickness and methods of lubricating an eye. The disclosure also provides methods of maintaining integrity of an eye's tear film layers which increases the eye's lipid layer thickness and methods of recreating or building one or more layers of an eye's tear film.
Claims12
An ophthalmic suspension comprising
- i) an aqueous phase comprising water and one or more components selected from the group consisting of at least one wax ester, at least one anionic polar surfactant, at least one nonionic surfactant, at least one salt, and at least one phosphate;
- and
- ii) an oil phase comprising at least one mineral oil and, optionally, at least one wax ester,
- wherein the ophthalmic suspension exhibits a Zeta potential of from about −60 mV to about −110 mV.
1 more element
Dependencies are inferred from the claim text.