Microbiome related immunotherapies
AssigneeFinch Therapeutics Holdings LLC
InventorsJoseph Lobacki, Ulrich Thienel, Zain Kassam, Marina Santiago
Life of this patent
Estimating the term…
Abstract
The present invention generally relates to therapeutic compositions and methods for treating cancer patients. The compositions and methods can increase efficacy of an anti-cancer therapy, or treat, prevent, or inhibit an oncology-treatment induced condition (OTIC) induced by an anti-cancer therapy. The therapeutic compositions comprise microbial compositions and, optionally, an anti-cancer therapeutic agent. The methods comprise administering a therapeutic composition comprising a microbial composition and administering an anti-cancer therapy.
Claims20
A method for increasing efficacy of an anti-cancer therapy administered to a subject having a cancer, the method comprising orally administering to the subject a therapeutic composition comprising a microbial preparation, wherein the microbial preparation comprises a non-selected community of fecal bacteria harvested from a stool of a healthy human donor, and wherein the non-selected community of fecal bacteria is lyophilized.
A method for treating lung cancer in a subject in need thereof, the method comprising:
- administering a checkpoint inhibitor to the subject;
- and orally administering to the subject a capsule containing a lyophilized microbial preparation comprising a non-selected community of fecal bacteria harvested from a stool of a healthy human donor.
Dependencies are inferred from the claim text.