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US 12,005,071 B2Granted
Injectable antibiotic formulations and use thereof
AssigneeDechra Veterinary Products, LLC
InventorsNeil E. Paulsen, Gail L. Dempsey, Michael S. Daniel, Tiffany G. Tomlinson, Douglas I. Hepler, Raymond Petzold
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Abstract
Provided herein are pharmaceutically acceptable compositions containing macrolide antibiotics, in particular azithromycin. In particular, compositions containing azithromycin with low toxicity, especially for administration to felines, are provided herein.
Claims17
A non-aqueous composition, comprising:
- (i) a macrolide;
- (ii) at least two solvents;
- and
- (iii) a surfactant;
- wherein a first solvent is triacetin, and wherein the triacetin is present in an amount of about 23 to 70% w/w, wherein a second solvent is selected from the group consisting of a triglyceride, acetylated monoglyceride, propyldicaprylates/dicaprates and caprylic/capric triglycerides, and wherein the second solvent is present in an amount of about 20-60%.
2 more elements
Dependencies are inferred from the claim text.