Topical pharmaceutical composition comprising at least amitriptyline, for the treatment of peripheral neuropathic pain

A pharmaceutical composition for the topical treatment of chemotherapy-induced peripheral neuropathic pain comprising, in a pharmaceutically acceptable carrier suitable for topical application, from 10.5% to 30% by weight, relative to the total weight of the composition, of amitriptyline or a pharmaceutically acceptable salt thereof, from 2% to 8% by weight of one or more surfactants chosen from sorbitan esters, glycerol esters, and mixtures of these compounds, —from 15% to 25% by weight of one or more fatty substances chosen from mineral oils, fatty acids, waxes and mixtures of these compounds, —from 0.1% to 4% by weight of one or more gelling agents chosen from carboxyvinyl polymers, —from 7% to 15% by weight of one or more hydrating active agents, —optionally from 0 to 3% by weight of one or more preservatives, —optionally from 0 to 1% by weight of one or more pH adjusters, and —water;

• wherein the amitriptyline or the pharmaceutically salt thereof is the sole agent for treating neuropathic pain.