System with improved seal between a liquid container and a manifold

A system comprising:

• a liquid container, configured to hold a liquid, comprising an opening, a rim surrounding the opening such that the diameter of the opening decreases towards an interior of the liquid container to form a conically shaped inclined inner peripheral support surface, and a first pressure exposure surface;
• a manifold comprising a circumferential sealing protrusion having a conically shaped inclined outer peripheral sealing surface configured to form a seal when directly in contact with the conically shaped inclined inner peripheral support surface of the liquid container without an intervening elastic sealing material, an aspirating tube configured to aspirate liquid from the liquid container, a valve configured to fill the liquid container, and a second pressure exposure surface;
• and
• a pressure generating element, configured to be moved by a user between a closed position and an open position, comprising a circumferential first pressure applying surface and a second circumferential pressure applying surface,
• wherein the first pressure applying surface contacts the pressure exposure surface of the container and the second pressure applying surface contacts the second pressure exposure surface of the manifold in the open position, and wherein the first and second pressure applying surfaces apply force to the first and second pressure exposure surfaces in the closed position to press the outer peripheral sealing surface of the manifold onto the inner peripheral support surface of the liquid container, forming a sealed connection between the liquid container and the manifold.