Methods, systems, and devices for analyzing lung imaging data
AssigneePulmonx Corporation
InventorsSri Radhakrishnan, Ryan Olivera
Life of this patent
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Abstract
Devices, methods, and systems are provided for analyzing lung imaging data. A server computing device receives imaging data of a lung over a network from a client computing device and analyzes the imaging data to identify lung, airways, and blood vessels, segment the lung into lobes, subtract airways, calculate volumes, calculate emphysema scores, identify fissure locations, calculate fissure completeness scores. A reconstruction of the fissures indicating locations where the fissures are incomplete and a report comprising fissure scores, volumes, and emphysema scores are created.
Claims23
A method for analyzing computerized tomography data of a lung, the method comprising:
- receiving by a server computing device computerized tomography data of a lung over a network from a client computing device at a different location;
- analyzing the computerized tomography data, wherein analyzing the computerized tomography data comprises:
- identifying the lung and airways;
- segmenting the lung into separate lobes;
- subtracting airways until at least the third generation;
- calculating volumes of the lobes;
- calculating emphysema scores for the lobes based on density masks;
- identifying fissure locations;
- calculating a fissure completeness score for the fissures;
- and
- creating a report comprising fissure completeness scores, volumes, and emphysema scores, wherein the report further comprises a two-dimensional graphical representation of the lung with the lobes identified, wherein the lobes are shaded or colored in the two-dimensional graphical representation to indicate the emphysema score;
- and wherein the fissures are identified in the two-dimensional graphical representation with lines that indicate the fissure completeness scores.
A method for analyzing computerized tomography data of a lung, the method comprising:
- receiving by a server computing device computerized tomography data of a lung over a network from a client computing device at a different location;
- analyzing the computerized tomography data, wherein analyzing the computerized tomography data comprises:
- identifying the lung and airways;
- segmenting the lung into separate lobes;
- subtracting airways until at least the third generation;
- calculating volumes of the lobes;
- calculating emphysema scores for the lobes based on density masks;
- identifying fissure locations;
- calculating a fissure completeness score for the fissures;
- determining airway diameters for lobar bronchi, segmental bronchi, and sub-segmental bronchi for each lobe;
- determining a distance from an ostium to a distal carina for the lobar bronchi, segmental bronchi, and sub-segmental bronchi;
- and
- creating a report comprising fissure completeness scores, volumes, emphysema scores, and the determined airway diameters and distances;
- wherein the report comprises a potential treatment site and a suggested implantable endobronchial valve having a diameter and length matching the diameter and distance determined for the potential treatment site.
A method for analyzing computerized tomography data of a lung, the method comprising:
- receiving by a server computing device computerized tomography data of a lung over a network from a client computing device at a different location;
- analyzing the computerized tomography data, wherein analyzing the computerized tomography data comprises:
- identifying the lung and airways;
- segmenting the lung into separate lobes;
- subtracting airways until at least the third generation;
- calculating volumes of the lobes;
- calculating emphysema scores for the lobes based on density masks;
- identifying fissure locations;
- calculating a fissure completeness score for the fissures;
- segmenting the lobes into separate lung segments;
- segmenting each lung segment into separate lung sub-segments;
- calculating volumes of the lung segments and sub-segments;
- calculating emphysema scores for the segments and sub-segments based on density masks;
- and
- creating a report comprising fissure completeness scores, and volumes and emphysema scores for each lung segment and sub-segments, wherein the report comprises a region of interest in contact with a location where a fissure is incomplete, a suggested therapeutic agent to be delivered at the region of interest, and a closest airway for treatment of the region of interest with the therapeutic agent, wherein the therapeutic agent is a sealant.
Dependencies are inferred from the claim text.