Systems and methods for therapeutic nasal neuromodulation

A method for treating a condition within a nasal cavity of a patient, the method comprising:

• providing a treatment device comprising:
• a multi-segment end effector operably associated with a shaft and comprising a first segment that is spaced apart from a separate and distinct second segment along a longitudinal axis along which a distal most portion of the shaft lies, wherein the second segment is positioned closer to a distal-most end of the shaft and the first segment is positioned closer to a proximal-most end of the shaft, each of the first and second segments is transformable between a retracted configuration and an expanded deployed configuration and comprises a respective architecture in the expanded deployed configuration, the first segment comprises a first architecture and the second segment comprises a second architecture that is different than the first architecture of the first segment, wherein the first segment comprises a first set of a plurality of flexible support elements that extend in a first outward direction relative to the longitudinal axis and are positioned within a first half of the first segment and cooperatively form an inwardly extending first concave shape when the first segment is in the expanded deployed configuration and a second set of a plurality of flexible support elements that extend in a second outward direction relative to the longitudinal axis and substantially opposite the first outward direction and are positioned within a second half of the first segment and cooperatively form an inwardly extending second concave shape substantially mirroring the first concave shape when the first segment is in the expanded deployed configuration, the first and second sets of plurality of flexible support elements cooperatively define the first architecture of the first segment when in the expanded deployed configuration, wherein the second segment comprises a third set of flexible support elements that cooperatively form the second segment and define the second architecture of the second segment when in the expanded deployed configuration, and wherein each flexible support element of the first, second, and third sets comprises one or more electrodes provided thereon;
• and a handle operably associated with the shaft, the handle having a first user-manipulatable mechanism for deployment of each of the first and second segments of the multi-segment end effector from the retracted configuration to the expanded deployed configuration and a second user-manipulatable mechanism, separate from the first user-manipulatable mechanism, for control of energy output by each of the first and second segments of the multi-segment end effector;
• advancing the multi-segment end effector to one or more target sites within the nasal cavity of the patient, the multi-segment end effector configured for delivering energy to one or more target sites within the nasal cavity;
• deploying, via user input with the first user-manipulatable mechanism on the handle, at least one of the first and second segments of the multi-segment end effector at the one or more target sites;
• and
• delivering energy from at least one of the first and second segments of the multi-segment end effector, via user input with the second user-manipulatable mechanism, to tissue at the one or more target sites.