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US 12,004,726 B2Granted
Sample collection device
AssigneeExact Sciences Corporation
InventorsGraham P. Lidgard, Michael J. Domanico, Keith Fourrier, James P. Light, II, Scott Castanon, Keith Kopitzke
Life of this patent
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Abstract
Provided herein is technology relating to collecting and preparing samples. For example, the technology relates particularly, but not exclusively, to devices, systems, and kits that allow a subject to collect and prepare a sample for analysis.
Claims18
A collection device containing a metered stool sample, the device comprising:
- a) a body comprising a sample collection chamber bounded on a distal end by a penetrable seal and bounded on a proximal end by a septum comprising an aperture, the penetrable seal being penetrable by a pipette tip or needle;
- b) a flexible sampling rod comprising a proximal portion and a distal portion, the sampling rod adapted to fit through and seal the aperture when the distal portion is in the sample collection chamber, wherein the distal portion comprises:
- i) an asymmetrical beveled tip at a distal end, the beveled tip having an apex at the circumference of the flexible sampling rod and configured to bend the flexible sampling rod away from collisions and/or to deflect collisions with an inserted pipette tip or needle;
- and
- ii) one or a plurality of metering ridges;
- wherein the sampling rod is positioned through the aperture in the septum such that the aperture in the septum is sealed by the sampling rod, and wherein the distal end of the sampling rod and a metered sample of stool are present in the sample collection chamber.
3 more elements
A system comprising:
- I) a collection device containing a metered stool sample, the device comprising:
- a) a body comprising a sample collection chamber bounded on a distal end by a penetrable seal and bounded on a proximal end by a septum comprising an aperture, the penetrable seal being penetrable by a pipette tip or needle;
- b) a flexible sampling rod comprising a proximal portion and a distal portion, the sampling rod adapted to fit through and seal the aperture when the distal portion is in the sample collection chamber, wherein the distal portion comprises:
- i) an asymmetrical beveled tip at a distal end, the beveled tip having an apex at the circumference of the flexible sampling rod and configured to bend the flexible sampling rod away from collisions and/or to deflect collisions with an inserted pipette tip or needle;
- and
- ii) one or a plurality of metering ridges;
- c) a solution in the sample collection chamber for preserving the metered sample of the stool;
- wherein the sampling rod is positioned through the aperture in the septum such that the aperture in the septum is sealed by the sampling rod, and wherein the distal end of the sampling rod and a metered sample of stool are present in the sample collection chamber;
- and
- II) an implement for withdrawing liquid from the sample collection chamber, the implement comprising a needle or pipette tip.
7 more elements
Dependencies are inferred from the claim text.