Systems and methods for assessing a likelihood of CTEPH and identifying characteristics indicative thereof

A non-transitory computer-readable storage medium comprising processor-executable instructions with which to perform an operation for assessing a likelihood of chronic thromboembolic pulmonary hypertension within a subject patient based upon an analysis of characteristics indicative of chronic thromboembolic pulmonary hypertension within an imaging study of the subject patient, the operation comprising:

• receiving an initial image set comprising a plurality of images from the imaging study of the subject patient and modifying one or more of the plurality of images from the initial image set to generate a modified image set comprising one or more modified images;
• identifying in at least one of the modified images of the modified image set one or more characteristics of one or more anatomical structures within a cardiac region of the subject patient indicative of chronic thromboembolic pulmonary hypertension;
• identifying in at least one of the modified images of the modified image set one or more characteristics of a pulmonary vasculature of the subject patient indicative of chronic thromboembolic pulmonary hypertension;
• identifying in at least one of the modified images of the modified image set one or more characteristics of a chronic abnormality in a lung of the subject patient indicative of chronic thromboembolic pulmonary hypertension;
• and
• assessing the one or more characteristics identified in the modified image set of (i) the one or more anatomical structures within the cardiac region of the subject patient indicative of chronic thromboembolic pulmonary hypertension, (ii) the pulmonary vasculature of the subject patient indicative of chronic thromboembolic pulmonary hypertension, and (iii) the chronic abnormality in the lung of the subject patient indicative of chronic thromboembolic pulmonary hypertension and computing, from this assessment, the likelihood of chronic thromboembolic pulmonary hypertension within the subject patient.

A system, comprising:

• an imaging modality for performing an imaging study on a subject patient;
• a hospital information system comprising a database storing information on a medical history of the subject patient;
• a workstation comprising a display screen;
• an image processing unit comprising a processor;
• and
• a memory storing an application program configured to perform, when executed by the processor, an operation for assessing a likelihood of chronic thromboembolic pulmonary hypertension within the subject patient based upon an analysis of characteristics indicative of chronic thromboembolic pulmonary hypertension within the imaging study of the subject patient, the operation comprising:
• receiving the initial image set comprising a plurality of images from the imaging study of the subject patient and modifying one or more of the plurality of images from the initial image set to generate a modified image set comprising one or more modified images;
• identifying in at least one of the modified images of the modified image set one or more characteristics of one or more anatomical structures within a cardiac region of the subject patient indicative of chronic thromboembolic pulmonary hypertension;
• identifying in at least one of the modified images of the modified image set one or more characteristics of a pulmonary vasculature of the subject patient indicative of chronic thromboembolic pulmonary hypertension;
• identifying in at least one of the modified images of the modified image set one or more characteristics of a chronic abnormality in a lung of the subject patient indicative of chronic thromboembolic pulmonary hypertension;
• and
• assessing the one or more characteristics identified in the modified image set of (i) the one or more anatomical structures within the cardiac region of the subject patient indicative of chronic thromboembolic pulmonary hypertension, (ii) the pulmonary vasculature of the subject patient indicative of chronic thromboembolic pulmonary hypertension, and (iii) the chronic abnormality in the lung of the subject patient indicative of chronic thromboembolic pulmonary hypertension and computing, from this assessment, the likelihood of chronic thromboembolic pulmonary hypertension within the subject patient.