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US 12,000,844 B2Granted
Diagnostic drug and diagnostic method for Alzheimer's disease
AssigneeSumitomo Pharma Co., Ltd.
InventorsAtsushi Ono, Yasuhiro Teranishi, Masanori Kusumoto, Masakazu Hashimoto, Shoji Kashiwabara, Maki Hashimoto
Life of this patent
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Abstract
The present invention provides a polypeptide consisting of any of the following amino acid sequences and useful for determining Alzheimer's disease: (1) the amino acid sequence shown in SEQ ID NO: 1; and (2) an amino acid sequence resulting from substitution, deletion, addition or insertion of one to several amino acids in the amino acid sequence shown in SEQ ID NO: 1.
Claims17
An antibody recognizing a S38AA polypeptide, wherein the S38AA polypeptide consists of the amino acid sequence of SEQ ID NO:
- 1, or an amino acid sequence resulting from substitution, deletion, addition, or insertion of one to several amino acids in the amino acid sequence of SEQ ID NO:
- 1, and wherein the antibody is
- (a) an antibody comprising the heavy chain variable region of SEQ ID NO:
- 4, and the light chain variable region of SEQ ID NO:
- 5,
- (b) an antibody comprising the heavy chain variable region of SEQ ID NO:
- 6, and the light chain variable region of SEQ ID NO:
- 7,
- (c) an antibody comprising the heavy chain variable region of SEQ ID NO:
- 8, and the light chain variable region of SEQ ID NO:
- 9,
- (d) an antibody comprising the heavy chain variable region of SEQ ID NO:
- 10, and the light chain variable region of SEQ ID NO:
- 11,
- (e) an antibody comprising the heavy chain variable region of SEQ ID NO:
- 12, and the light chain variable region of SEQ ID NO:
- 13,
- (f) an antibody comprising the heavy chain variable region of SEQ ID NO:
- 14, and the light chain variable region of SEQ ID NO:
- 15,
- (g) an antibody comprising the heavy chain variable region of SEQ ID NO:
- 16, and the light chain variable region of SEQ ID NO:
- 17,
- (h) an antibody comprising the heavy chain variable region of SEQ ID NO:
- 18, and the light chain variable region of SEQ ID NO:
- 19,
- (i) an antibody comprising the heavy chain variable region of SEQ ID NO:
- 20, and the light chain variable region of SEQ ID NO:
- 21, or
- (j) an antibody comprising the heavy chain variable region of SEQ ID NO:
- 22, and the light chain variable region of SEQ ID NO:
- 23.
29 more elements
Dependencies are inferred from the claim text.