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US 12,000,832 B2Granted
Marker composition for diagnosing or predicting prognosis of lung cancer based on exosome overexpressing GCC2 gene or protein
AssigneesKorea University Research and Business Foundation, Korea Advanced Institute of Science and Technology
InventorsHyun Koo Kim, Sung Hoi Hong, Yong Park, Yeon Ho Choi, Ji Ho Park, Byeong Hyeon Choi, Hye Sun Jeong
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Abstract
According to an embodiment of the present invention, a composition for diagnosing or predicting the prognosis of lung cancer is provided, the composition including a primer, probe, or antibody that specifically binds to a GRIP and coiled-coil domain-containing protein (GCC2) gene or protein in an exosome.
Claims2
A method for identifying a level of GCC2 expression, the method comprising below steps:
- (a) obtaining a blood sample from a suspected lung cancer subject;
- (b) separating an exosome from the blood sample;
- and
- (c) measuring an expression level of a GCC2 (GRIP and coiled-coil domain-containing protein) protein in the exosome.
1 more element
Dependencies are inferred from the claim text.