Method of treating autoimmune disease with antibodies against IL-33
AssigneeAnaptysBio, Inc.
InventorsRobert A. Horlick, David J. King, Andrew John McKnight
Life of this patent
Estimating the term…
Abstract
The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to interleukin-33 (IL-33). The invention provides an IL-33-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using the IL-33-binding agent to treat a disorder in a mammal that is responsive to IL-33 inhibition.
Claims12
A method of treating an autoimmune disease using an interleukin-33 (IL-33) binding protein comprising an immunoglobulin heavy chain comprising CDR1, CDR2, and CDR3 of SEQ ID NO:
- 136, and an immunoglobulin light chain comprising CDR1, CDR2, and CDR3 of SEQ ID NO:
- 171.
Dependencies are inferred from the claim text.