Method for producing diarylpyridine derivatives
AssigneeDaiichi Sankyo Company, Limited
InventorsYuichi Aki, Fumihiko Toriyama, Natsuki Sakurai, Ai Kameda, Tomokazu Ogura
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AssigneeDaiichi Sankyo Company, Limited
InventorsYuichi Aki, Fumihiko Toriyama, Natsuki Sakurai, Ai Kameda, Tomokazu Ogura
Estimating the term…
The present invention relates to a novel method for producing diarylpyridine derivatives, and the object of the present invention is to provide a novel, industrially useful method. The present inventors developed a novel method for synthesizing pyridine rings without using palladium, a strong base, or a high-temperature reaction. In particular, they successfully developed a method that can be used to synthesize iminium salts as intermediates, synthesize cyano compounds from these iminium salts, and cyclize the cyano compounds into pyridines under very mild reaction conditions.
A production method comprising the step of reacting a compound represented by Formula (I):
A production method comprising the steps of:
A production method, comprising reacting a compound represented by Formula (VI):
Dependencies are inferred from the claim text.