WDR5 inhibitors and modulators

A compound of formula (I)

• or a pharmaceutically acceptable salt thereof, wherein:
• n is 1;
• R1 is —(CRaRb)-G1;
• G1 is a 6 or 5-membered aromatic ring optionally containing 1-2 nitrogen atoms, wherein G1 is substituted with 1-3 substituents independently selected from the group consisting of —OC1-4alkyl, C1-4alkyl, halogen, and C3-6cycloalkyl;
• Ra is C1-4alkyl, C3-6cycloalkyl, or hydrogen;
• Rb is hydrogen;
• R2a, R2b, R3a, and R3b are each hydrogen;
• R4 is a 5 or 6-membered aromatic ring optionally containing 1-2 nitrogen atoms, wherein R4 is substituted with 2, 1, or 3 substituents independently selected from the group consisting of C1-4haloalkyl, C1-4alkyl, and halogen;
• R5 is hydrogen;
• R6 is hydrogen;
• R7a and R7b are each hydrogen;
• and
• R8 is a 5-membered heterocyclic ring containing 2-3 heteroatoms and 2 or 1 double bonds, wherein one of the 2-3 heteroatoms is a nitrogen and the remaining heteroatoms are independently selected from nitrogen and oxygen, wherein R8 is optionally substituted with 1-3 substituents independently selected from the group consisting of C1-4alkyl, imino, C1-4haloalkyl, —NH(C1-4alkyl), halogen, cyano, NH2, —N(C1-4alkyl)2, C3-6cycloalkyl, and —C1-3alkylene-C3-6cycloalkyl.