Synthetic sphingolipid-like molecules, drugs, methods of their synthesis and methods of treatment
AssigneeThe Regents of the University of California
InventorsAimee L. Edinger, Stephen Hanessian
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Abstract
Small molecules comprised of azacyclic constrained sphingolipid-like compounds and methods of their synthesis are provided. Formulations and medicaments are also provided that are directed to the treatment of disease, such as, for example, neoplasms, cancers, and other diseases. Therapeutics are also provided containing a therapeutically effective dose of one or more small molecule compounds, present either as pharmaceutically effective salt or in pure form, including, but not limited to, formulations for oral, intravenous, or intramuscular administration.
Claims9
A method for treating a cancer, comprising:
- administering a pharmaceutical formulation to a human subject, the formulation containing:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.