Method and apparatus for magnetic nanoparticles development with ultra-small size, uniformity and monodispersity

A method of making magnetic nanoparticles through the utilization of a microfluidic reactor,

• wherein the microfluidic reactor comprises:
• a first end,
• a second end,
• a spiral shaped microchannel between the first end and the second end,
• a first inlet and a second inlet, wherein the first inlet and the second inlet are positioned at the first end, and
• an outlet positioned at the second end, and wherein the method comprises:
• applying a magnetic nanoparticle precursor solution into the first inlet of the microfluidic reactor through a first flow rate;
• and
• applying a reducing agent into the second inlet of the microfluidic reactor through a second flow rate,
• wherein the applying of the magnetic nanoparticle precursor solution occurs after the applying of the reducing agent, and
• wherein the magnetic nanoparticles are produced in the microfluidic reactor and collected from the outlet of the microfluidic reactor.

A method of making magnetic nanoparticles through the utilization of a microfluidic reactor,

• wherein the microfluidic reactor comprises:
• a first end,
• a second end,
• a spiral shaped microchannel between the first end and the second end,
• wherein the microchannel comprises widths ranging from 50 μm to 500 μm and heights ranging from 50 μm to 500 μm,
• a first inlet and a second inlet, wherein the first inlet and the second inlet are positioned at the first end, and
• an outlet positioned at the second end, and wherein the method comprises:
• applying a magnetic nanoparticle precursor solution into the first inlet of the microfluidic reactor through a first flow rate;
• and
• applying a reducing agent into the second inlet of the microfluidic reactor through a second flow rate,
• wherein the magnetic nanoparticles are produced in the microfluidic reactor and collected from the outlet of the microfluidic reactor.

A method of making magnetic nanoparticles through the utilization of a microfluidic reactor,

• wherein the microfluidic reactor comprises:
• a first end,
• a second end,
• a spiral shaped microchannel between the first end and the second end,
• a first inlet and a second inlet, wherein the first inlet and the second inlet are positioned at the first end, and
• an outlet positioned at the second end, and wherein the method comprises:
• applying a magnetic nanoparticle precursor solution into the first inlet of the microfluidic reactor through a first flow rate;
• and
• applying a reducing agent into the second inlet of the microfluidic reactor through a second flow rate,
• wherein the magnetic nanoparticles are produced in the microfluidic reactor and collected from the outlet of the microfluidic reactor, and
• wherein the magnetic nanoparticles have sizes of less than about 10 nm in diameter.

A method of making magnetic nanoparticles through the utilization of a microfluidic reactor,

• wherein the microfluidic reactor comprises:
• a first end,
• a second end,
• a spiral shaped microchannel between the first end and the second end,
• a first inlet and a second inlet, wherein the first inlet and the second inlet are positioned at the first end, and
• an outlet positioned at the second end, and wherein the method comprises:
• applying a magnetic nanoparticle precursor solution into the first inlet of the microfluidic reactor through a first flow rate;
• and
• applying a reducing agent into the second inlet of the microfluidic reactor through a second flow rate,
• wherein the spiral shaped microchannel provides laminar flow of the magnetic nanoparticle precursor solution and the reducing agent through the microfluidic reactor, and
• wherein the magnetic nanoparticles are produced in the microfluidic reactor and collected from the outlet of the microfluidic reactor.