Methods and systems for disease treatment using electrical stimulation
AssigneeNevro Corporation
InventorsGary Heit, Bradford Evan Gliner
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Abstract
Systems for disease treatment using electrical stimulation are disclosed. A representative method for treating a patient includes changing an activity, expression, or both activity and expression of a fast sodium channel, a glial cell, or both a fast sodium channel and a glial cell of the patient by applying to a target neural population of the patient an electrical therapy signal having a frequency in a frequency range of 1.5 kHz to 100 kHz.
Claims42
A method for treating pain in a patient by changing an activity of a glial cell of the patient, comprising:
- programming a signal generator to deliver an electrical therapy signal to a neural population located in the patient's spinal cord via an implanted signal delivery element to treat the patient, wherein the electrical therapy signal has a frequency in a frequency range from 2 Hz to 100 kHz, and wherein the electrical therapy signal produces changes in the activity of the glial cell of the patient.
A method for treating pain in a patient by changing an activity of a glial cell of the patient, comprising:
- using a signal generator to generate an electrical therapy signal;
- transmitting the electrical therapy signal to a signal delivery element positioned proximate to a neural population in the patient's spinal cord;
- applying the electrical therapy signal to the neural population, wherein the electrical therapy signal produces changes in the activity of the glial cell to reduce pain in the patient.
A method for treating pain in a patient by changing an activity of a glial cell of the patient, comprising:
- programming a signal generator to deliver an electrical therapy signal to a neural population located in the patient's dorsal horn and/or dorsal column via an implanted signal delivery element to treat the patient, wherein the electrical therapy signal has a frequency in a frequency range from 2 Hz to 100 kHz, and wherein the electrical therapy signal produces changes in the activity of the glial cell to reduce pain in the patient.
A method for treating pain in a patient by changing an expression of a glial cell of the patient, comprising:
- programming a signal generator to deliver an electrical therapy signal to a neural population located in the patient's spinal cord via an implanted signal delivery element to treat the patient, wherein the electrical therapy signal has a frequency in a frequency range from 2 Hz to 100 kHz, and wherein the electrical therapy signal produces changes in the expression of the glial cell of the patient.
A method for treating pain in a patient by changing an expression of a glial cell of the patient, comprising:
- using a signal generator to generate an electrical therapy signal;
- transmitting the electrical therapy signal to a signal delivery element positioned proximate to a neural population in the patient's spinal cord;
- applying the electrical therapy signal to the neural population, wherein the electrical therapy signal produces changes in the expression of the glial cell that reduces pain in the patient.
Dependencies are inferred from the claim text.