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US 11,998,659 B2Granted
Bioimplant with evanescent coating film
AssigneeKYOCERA Corporation
InventorsTakao Hotokebuchi, Iwao Noda
Life of this patent
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Abstract
To provide a bioimplant capable of controlling a rate of an antibacterial agent and an antibiotic to be eluted from the coating film. An evanescent coating film made of a calcium phosphate-based material having crystallinity of 10% to 90% is formed at a predetermined area of the bioimplant and an antibacterial agent or an antibiotic is contained in the coating film to suppress adhesion of bacteria.
Claims11
A method of manufacturing a bioimplant, comprising:
- providing a base material of the bioimplant;
- mixing a calcium phosphate-based material and an inorganic antibacterial agent to provide a mixed material before forming a thermal sprayed film;
- and
- forming the thermal sprayed film on at least a part of a surface of the base material by spraying the mixed material on the at least a part of a surface of the base material, the thermal sprayed film comprising the calcium phosphate-based material supporting the inorganic antibacterial agent,
- wherein the inorganic antibacterial agent comprises a silver material, and
- wherein an evanescence period of the thermal sprayed film is configured to be a predetermined period in the range of 6 weeks to 120 months by selecting a combination of a thickness and a crystallinity of the thermal sprayed film such that silver ions are eluted during the predetermined period.
3 more elements
A method of manufacturing a bioimplant, comprising:
- providing a base material of the bioimplant;
- spraying a mixed material containing an inorganic antibacterial agent and a calcium phosphate-based material to apply a coating film onto the base material, wherein the mixed material is provided by mixing the calcium phosphate-based material and the inorganic antibacterial agent before the spraying, and wherein the spraying comprises a thermal spraying process using a plasma spraying method or a flame spraying method,
- wherein the inorganic antibacterial agent comprises a silver material, and
- wherein an evanescence period of the coating film is configured to be a predetermined period in the range of 6 weeks to 120 months by selecting a combination of a thickness and a crystallinity of the coating film such that silver ions are eluted during the predetermined period.
1 more element
Dependencies are inferred from the claim text.