Modified release coated capsules
AssigneeTillotts Pharma AG
InventorsRoberto Carlos Bravo Gonzaléz, Felipe José Oliveira Varum, Thomas Buser
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Abstract
Herein described is a modified release coated capsule and a process to obtain that capsule.
Claims10
A capsule filled with a liquid material comprising a body, a cap and a gap therebetween, characterized in that said capsule body and capsule cap define a capsule shell, wherein capsule shell is selected from the group consisting of a hydroxypropylmethyl cellulose (HPMC) shell, a pullulan shell, and a polyvinyl alcohol (PVA)-based shell, and said capsule further comprises a band seal and a modified release coating applied to said capsule shell, further wherein said band seal is a gelatin band sealing the gap between said capsule body and capsule cap, and said modified release coating is an enteric coating that includes an enteric film forming agent, wherein the enteric film forming agent is present in an amount ranging from about 1 mg/cm2 to about 4.0 mg/cm2 of the modified release coating and is selected from the group consisting of acrylate polymers, cellulose polymers, polyvinyl-based polymers and mixtures thereof, further wherein there is no pre-coating between said capsule shell and said modified release coating, further wherein said enteric coating renders said capsule resistant against stomach acid while completely releasing its liquid material contents under intestinal tract conditions.
Dependencies are inferred from the claim text.