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US 11,998,612 B2Granted
Method for conjugating antibody and physiologically active substance
AssigneeNovelty Nobility Inc.
InventorsTae Hyeon Yoo, Jisoo Park, Yumi Lee
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AssigneeNovelty Nobility Inc.
InventorsTae Hyeon Yoo, Jisoo Park, Yumi Lee
Estimating the term…
An antibody conjugating peptide including an amino acid having a photoreactive functional group, a physiologically active substance modified with the conjugating peptide, and an antibody conjugate having an antibody linked to the physiologically active substance are disclosed. When the physiologically active substance modified with the conjugating peptide is linked to the antibody, the conjugation efficiency between the antibody and the physiologically active substance is remarkably improved as compared to that of the conventional art, and thus, the drug may be firmly bound without impairing the specificity of the antibody, thereby making it possible to accelerate commercialization of the antibody conjugate.
A substance modified with an Fc site-specific conjugating peptide mutant, wherein the substance is linked to the Fc site-specific conjugating peptide mutant either directly or via a linker,
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