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US 11,998,609 B2Granted
Self-assembling antiviral prodrugs
AssigneeThe Johns Hopkins University
InventorsHonggang Cui, Charles Williams Flexner, Maya Monroe, Han Wang
Life of this patent
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Abstract
Disclosed are therapeutic self-assembling molecules including a peptide sequence conjugated to one or more antiviral therapeutics to form a peptide-based antiviral prodrug capable of self-assembly into supramolecular structures with varying morphology in aqueous solutions, which can be injected subcutaneously or intramuscularly for the long-acting treatment of chronic viral infections.
Claims8
A composition comprising a peptide-based antiretroviral therapeutic (ARV) prodrug selected from the group consisting of:
Dependencies are inferred from the claim text.