Method for treating nociceptive pain and burns with brazilian green propolis alcohol extract

A method for treating nociceptive pain from a burn, comprising:

• administering to a subject in need of treatment for nociceptive pain from a burn afferently transmitted via non-myelinated C fibers a composition comprising an ethanol extract of Brazilian green propolis (′BGP″),
• wherein the ethanol extract of BGP is produced by extracting BGP with an aqueous solution of 60 to 80% ethanol,
• wherein the extraction is carried out at a pH between about 6 and about 8,
• wherein the composition comprises 1.0 to 5 wt % Artepillin C, 1-5 wt % drupanin, 5 wt % baccharin, and less than 0.01 wt ° % a fortriononetin;
• wherein the dose is administered by a method selected from the group consisting of topical, oral, parenteral, respiratory, and combinations thereof;
• wherein the dose ranges from 0.01 to 100 mg/kg/day;
• and
• wherein the early phase neurogenic analgesic response is stronger at a dose of 50 mg/kg than the response at 100 mg/kg.