Composition comprising lipoic acid and vitamin D for the prevention and the treatment of neurodegenerative diseases and peripheral neuropathies

A method for reducing oxidative stress in an astrocyte, comprising administering to the astrocyte a composition comprising a mixture of:

• (I) lipoic acid or a derivative thereof, or an acceptable pharmaceutical salt of lipoic acid or a derivative thereof;
• (II) a vitamin of group D or a derivative thereof, wherein said (II) vitamin of group D is selected from among:
• vitamin D3 or a derivative thereof, vitamin D2 or a derivative thereof and a mixture thereof;
• wherein:
• (a) the lipoic acid or a derivative thereof is 98% to 99.9% of the mixture by weight, and
• (b) the vitamin D3 and/or vitamin D2, or a derivative thereof, is 0.001% to 1% 0.001% to 10% of the mixture by weight and, optionally, said composition comprises at least one pharmaceutical additive and/or excipient.