Micelle comprising benzimidazole-carbohydrate conjugate compound, preparation method thereof and use thereof as anticancer agent or antiviral agent comprising the same
AssigneeBiometrix Technology Inc.
InventorsTaisun Kim, Keumsoo Song, Junghun Kim
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Abstract
Disclosed herein are a micelle comprising a benzimidazole-carbohydrate conjugate compound represented by the following chemical formula 1, a preparation method thereof, and use thereof as an anticancer agent or an antiviral agent comprising the same: in the above formula, R1, R2, R3 and X are the same as those defined in the disclosure and claims.
Claims12
A micelle comprising a benzimidazole-carbohydrate conjugate compound represented by the following chemical formula 1 and a benzimidazole-ammonium compound represented by the following chemical formula 1b:
- wherein, the —NH—R1 moiety has one of the following structures:
- the benzimidazole moiety has one of the following structures:
- and
- Y− is a conjugate base of acid (H+) and is selected from Cl−, Br−, I−, F−, NO3−, CH3COO−, HCOO−, HCO3−, CO32−, H2PO4−, HPO42−, HSO4−, SO42−, or ClO4−.
A preparation method of a micelle, comprising mixing a benzimidazole-carbohydrate conjugate compound represented by the following chemical formula 1 with a benzimidazole-ammonium compound represented by the following chemical formula 1b:
- wherein, the —NH—R1 moiety has one of the following structures:
- the benzimidazole moiety has one of the following structures:
- Y− is a conjugate base of acid (H+) and selected from Cl−, Br−, I−, F−, NO3−, CH3COO−, HCOO−, HCO3−, CO32−, H2PO4−, HPO42−, HSO4−, SO42−, or ClO4−.
Dependencies are inferred from the claim text.