Intermittent monitoring

A non-transitory computer-readable medium comprising instructions thereon that, when executed by at least one processor, causes the at least one processor to perform operations comprising:

• during a first time period, monitoring glucose concentrations of a patient continuously measured by a continuous glucose monitoring (CGM) system adapted to be worn by the patient, the monitoring comprising receiving a plurality of first glucose information of the patient from the CGM system, wherein the plurality of first glucose information is indicative of the glucose concentrations of the patient at a plurality of times during the first time period;
• during the first time period, receiving a plurality of first non-glucose information of the patient from an activity monitor adapted to be worn by the patient, wherein the plurality of first non-glucose information is indicative of physical activity of the patient corresponding to the plurality of times during the first time period;
• determining relationships between the plurality of first glucose information and the plurality of first non-glucose information by correlating the physical activity of the patient with corresponding impacts on the glucose concentrations of the patient as the glucose concentrations vary;
• determining, during a second time period, that glucose information from the CGM system is not available;
• during the second time period in which glucose information from the CGM system is not available, receiving second non-glucose information of the patient from the activity monitor, wherein the second non-glucose information is indicative of physical activity of the patient corresponding to the second time period;
• estimating, in real time, second glucose information of the patient for the second time period based upon the second non-glucose information of the patient and the determined relationships between the plurality of first glucose information and the plurality of first non-glucose information;
• and
• electronically delivering, during the second time period, a notification about the second glucose information.