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US 11,994,517 B2Granted
Analytical assay reaction cartridge containing magnetic capture beads and methods of production and use thereof
AssigneeSiemens Healthcare Diagnostics Inc.
InventorsAaron Kauffmann, Jon Stradinger
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Abstract
Analytical assay reaction cartridges, kits containing same, and methods of production and use thereof are disclosed. These cartridges include a magnetic assembly that surrounds at least a portion of a sample read window on the cartridge. The cartridge also includes an analytical reagent positioned therewithin, wherein the analytical reagent comprises magnetic beads coated with at least one anti-red blood cell antibody.
Claims26
An analytical assay reaction assembly, comprising:
- an analytical assay reaction cartridge having a housing that comprises a reaction chamber, an inlet for introducing a liquid test sample into the reaction chamber, and a sample read window formed through a portion of the reaction chamber, wherein the sample read window has a shape with an outer edge that surrounds the shape of the sample read window that extends through the portion of the reaction chamber;
- at least one solid analytical reagent, wherein the solid analytical reagent comprises magnetic beads coated with at least one anti-human red blood cell antibody, and wherein the solid analytical reagent is soluble in a liquid reagent;
- and
- a magnetic assembly comprising a permanent magnet;
- and
- wherein at least one contact point of the magnetic assembly is disposed substantially adjacent to at least one contact point on the outer edge of the sample read window of the analytical assay reaction cartridge.
3 more elements
Dependencies are inferred from the claim text.