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US 11,993,649 B2Granted
Antibodies against MFAP4
AssigneeSyddansk Universitet
InventorsGrith Lykke Sørensen, Anders Schlosser, Uffe Holmskov
Life of this patent
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Abstract
The present invention relates to antibodies, including humanized antibodies that bind human Microfibrillar-associated protein 4 (MFAP4). The invention also relates to uses of such antibodies.
Claims17
A protein ligand, comprising:
- (a) a light chain variable region comprising the amino acid sequence of SEQ ID NO:
- 3, or a sequence having at least 90% sequence identity to SEQ ID NO:
- 3;
- and
- (b) a heavy chain variable region comprising the amino acid sequence of SEQ ID NO:
- 4, or a sequence having at least 90% sequence identity to SEQ ID NO:
- 4;
- the protein ligand comprising:
- (a) a light chain variable region comprising a CDR 1 region according to SEQ ID NO:
- 9, a CDR 2 region according to SEQ ID NO:
- 10, and a CDR 3 region according to SEQ ID NO:
- 11;
- and
- (b) a heavy chain variable region comprising a CDR 1 region according to SEQ ID NO:
- 12, a CDR 2 region according to SEQ ID NO:
- 13, and a CDR 3 region according to SEQ ID NO:
- 14.
14 more elements
Dependencies are inferred from the claim text.