Inhibitors of KRAS G12C and methods of using the same

A compound having a structure of formula (I)

• wherein
• A is independently N or CH;
• W is independently N or CH;
• wherein one or both of A and W is N;
• R1 and R2 are independently a branched or a linear —C1—C6 alkyl, wherein the —C1-C6 alkyl is substituted with one or more of independently selected from halo, trifluoromethyl, trifluoromethoxy, hydroxy, alkoxy, nitro, cyano, alkylamino, —C1—C8 alkyl, —C2—C8 alkenyl, —C2—C8 alkynyl, —NC, amino, —CO2H, —CO2C1—C8_alkyl, —OOOC1—C8_alkyl, cycloalkyl, —C3—C10 heterocycloalkyl, —C5—C10 aryl, and —C5—C10 heteroaryl;
• R3is phenyl substituted by 1 or 2 R5 substituents;
• R5 is independently selected from one or more halo, —OH, or NH2;
• R4 is halo;
• or
• a stereoisomer thereof, an atropisomer thereof, a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable salt of the stereoisomer thereof, or a pharmaceutically acceptable salt of the atropisomer thereof.