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US 11,993,589 B2Granted
Prodigiosin analogs and methods of use
AssigneeInstitute For Cancer Research
InventorsWafik S. El-Deiry, Xiaobing Tian
Life of this patent
Estimating the term…
Abstract
Prodigiosin analogs which reactivate the p53 pathway are provided, as well as compositions of these compounds, and methods for reactivation of the p53 pathway using these compounds are provided. The prodigiosin analogs may be used to treat cancer in which p53 mutation plays a role, including prostate cancer, breast cancer, kidney cancer, ovarian cancer, lymphoma, leukemia, and glioblastoma, among others.
Claims8
A method of treating colorectal cancer in a subject, the method comprising administering to the subject a compound of formula:
- or tautomer or solvate thereof, or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.