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US 11,993,584 B2Granted
Solid forms of an azolopyrimidine compound
AssigneeArcus Biosciences, Inc.
InventorsJenna Leigh Jeffrey, Manmohan Reddy Leleti, Dillon Harding Miles, Jay Patrick Powers
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Abstract
The present invention provides solid forms, solvates and hydrates of 3-[2-amino-6-(1-{[6-(2-hydroxypropan-2-yl)pyridin-2-yl]methyl}-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl]-2-methylbenzonitrile (Compound I), and methods of making and using the same.
Claims21
A solid form of Compound I:
- wherein the solid form is characterized by an XRPD pattern comprising one or more peaks at 6.9, 8.0, 8.2, 12.5, 12.7, 14.8, 15.0, 15.7, 16.8, 18.1, 18.8, 19.2, 20.6, 21.1, 21.8, 24.9, 27.1, or 27.7 degrees 2θ (±0.1 degrees 2θ), wherein the XRPD is made using CuKα1 radiation, or a hydrate or solvate thereof.
A solid form of Compound I:
- characterized by an X-ray powder diffraction pattern (XRPD) substantially in accordance with that of FIG. 5.
A solid form of Compound I,
- characterized by an X-ray powder diffraction pattern (XRPD) substantially in accordance with that of FIG. 7.
Dependencies are inferred from the claim text.