Pyrazole and imidazole compounds for inhibition of IL-17 and RORgamma

A compound of the formula:

• wherein:
• n is 0, 1, or 2;
• R1 is cyano, fluoro, —CF3, or —C(O)Ra, wherein:
• Ra is hydroxy or amino;
• or
• alkoxy(C≤6), alkylamino(C≤6), dialkylamino(C≤6), or a substituted version of any of these groups;
• R2 is hydrogen;
• or
• alkyl(C≤12), cycloalkyl(C≤12), alkenyl(C≤12), alkynyl(C≤12), aryl(C≤18), aralkyl(C≤18), heteroaryl(C≤18), heteroaralkyl(C≤18), or a substituted version of any of these groups;
• R2′ is hydrogen;
• R3 is alkyl(C≤12), alkenyl(C≤12), aryl(C≤12), aralkyl(C≤12), or a substituted version of any of these groups;
• R4 and R5 are each independently absent;
• or
• cycloalkyl(C≤12), heterocycloalkyl(C≤12), aryl(C≤12), aralkyl(C≤12), heteroaryl(C≤12), heteroaralkyl(C≤12), -arenediyl(C≤12)-alkyl(C≤12), -arenediyl(C≤12)-aryl(C≤12), -arenediyl(C≤12)-heteroaryl(C≤12), -arenediyl(C≤12)-heterocycloalkyl(C≤12), -arenediyl(C≤12)-cyclo-alkyl(C≤12), -heteroarenediyl(C≤12)-alkyl(C≤12), -heteroarenediyl(C≤12)-aryl(C≤12), -hetero-arenediyl(C≤12)-heteroaryl(C≤12), -heteroarenediyl(C≤12)-hetero-cycloalkyl(C≤12), -heteroarenediyl(C≤12)-cycloalkyl(C≤12), -heterocycloalkanediyl(C≤12)-aryl(C≤12), -heterocycloalkanediyl(C≤12)-heteroaryl(C≤12), or a substituted version of any of these groups;
• or
• a group of the formula:
• wherein 1 and m are each 0, 1, 2, or 3;
• R6 is absent or amino;
• or
• alkylamino(C≤12), dialkylamino(C≤12), cycloalkylamino(C≤12), dicycloalkylamino(C≤12), alkyl(cycloalkyl)amino(C≤12), arylamino(C≤12), diarylamino(C≤12), alkyl(C≤12), cycloalkyl(C≤12), -alkanediyl(C≤12)-cycloalkyl(C≤12), -alkanediyl(C≤18)-aralkoxy(C≤18), heterocycloalkyl(C≤12), aryl(C≤18), -arenediyl(C≤12)-alkyl(C≤12), aralkyl(C≤18), -arenediyl(C≤18)-heterocycloalkyl(C≤12), heteroaryl(C≤18), -heteroarenediyl(C≤12)-alkyl(C≤12), heteroaralkyl(C≤18), acyl(C≤12), alkoxy(C≤12), or a substituted version of any of these groups;
• or a pharmaceutically acceptable salt thereof.