Composite material for rapid blood clotting and preparation method thereof

A composite material for blood clotting, wherein the composite material is formed by using the following raw materials in parts by weight:

• 8 to 20 parts of chitosan, 7 to 14 parts of salicylaldehyde, 8 to 16 parts of 2-aminoisonicotinic acid, 1.5 to 3.5 parts of ferrous sulfate (Fe2+ sulphate), 3 to 5 parts of a dopa compound, and 10 to 15 parts of disodium hydrogen phosphate;
• wherein a chitosan-based Fe2+ complex is formed by introducing the 2-aminoisonicotinic acid onto a molecular chain of the chitosan through an acylation reaction to obtain chitosan-amino isonicotinic acid graft, forming a Schiff base by condensation of the salicylaldehyde and amino groups of the 2-aminoisonicotinic acid, and combining the Schiff base with the ferrous sulfate;
• wherein the composite material comprises:
• a charge transfer compound formed according to the dopa ingredient and the chitosan-based Fe2+ complex;
• wherein the composite material has a porous structure formed by interacting hydrogen phosphate anions of the disodium hydrogen phosphate with protonated amino groups of the chitosan to generate electrostatic and hydrogen bond effects;
• wherein the composite material is in a form of solid;
• and the composite material forms a hydrogel after absorbing liquid;
• a molecular mass of the chitosan is 50˜300 kilodaltons (KDa), and a degree of deacetylation of the chitosan is 80˜95%.