Composition for prevention or treatment of neurodevelopmental disorder, neurologic diseases, or psychiatric diseases comprising extracellular vesicles derived from Micrococcus luteus

A method for alleviating or treating symptoms of a degenerative brain neurologic disease in a subject in need thereof, comprising administering a composition comprising vesicles derived from Micrococcus luteus as an active ingredient to the subject having the symptoms,

• wherein the disease is mediated by a NLR family pyrin domain containing 3 inflammasome (NLRP3 inflammasome),
• wherein the composition suppresses NLRP3 inflammasome formation,
• wherein the alleviating or treating symptoms is selected from the group consisting of suppression of progression of short-term and long-term cognitive impairments, restoration of spatial perceptual learning or memory, restoration of memory ability, suppressing memory ability loss induced by abnormal beta-amyloid (Aβ) protein, suppression of accumulated Aβ plaque, induction of neurogenesis, and protection of microstructure of dendrites to improve intercellular integrity, and
• wherein the degenerative brain neurologic disease is one or more diseases selected from the group consisting of Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and epilepsy.