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US 11,992,477 B2Granted
Pharmaceutical combination, composition, and combination preparation comprising glucokinase activator and SGLT-2 inhibitor and preparation methods and uses thereof
AssigneeHua Medicine (Shanghai) Ltd.
InventorsLi Chen, Yongguo Li, Gaosen Wang, Huisheng Gao
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Abstract
The present invention relates to a pharmaceutical combination, comprising a glucokinase activator or a pharmaceutically acceptable salt, isotopic label, crystal form, hydrate, solvate, diastereomer, or enantiomer thereof and an SGLT-2 inhibitor. The present invention further relates to a pharmaceutical composition, a fixed-dose combination preparation, and preparation methods and uses thereof.
Claims63
A fixed dose combination formulation, comprising:
- (a) a glucokinase activator, which is a compound represented by the following formulae, or a pharmaceutically acceptable salt, an isotope labeled analogue, a crystalline form, a hydrate, a solvate, or a diastereomeric or enantiomeric form thereof,
- (b) a SGLT-2 inhibitor;
- and
- (c) one or more excipients.
1 more element
Dependencies are inferred from the claim text.