Back to results
US 11,992,475 B1Granted
Application of Z-ligustilide in resisting rotaviruses
AssigneeGuangdong Medical University
InventorsLijun Song, Wenchang Zhao
Life of this patent
Estimating the term…
Abstract
The present invention discloses an application of Z-ligustilide in resisting rotaviruses, and relates to the technical field of medicines. Z-ligustilide has no drug toxicity to cells at 60-95 μM and can effectively inhibit rotavirus biosynthesis at 70-85 μM. Z-ligustilide plays a role in resisting rotavirus biosynthesis by inhibiting structural protein VP6, and has no effect of adsorbing and directly killing rotaviruses, which provides a new way for resisting rotaviruses.
Claims3
A method of inhibiting rotavirus biosynthesis, comprising:
- providing Z-ligustilide, wherein an effective concentration of the Z-ligustilide is 70-85 μM.
Dependencies are inferred from the claim text.