P2RX7 modulators in therapy

A compound chosen from compounds of formula (I), their enantiomers and their pharmaceutically acceptable salts:

• in which:
• R1 represents a C1 -C14 alkyl, a cycloalkyl group, a phenyl or biphenyl group, a benzyl group or a heteroaryl group selected from the group consisting of pyridine and thiophene, wherein said phenyl, biphenyl, benzyl or heteroaryl group is optionally substituted with at least one group selected from the group consisting of:
• halogen atoms;
• C1-C6 alkoxy radicals;
• C1-C6 alkyl radicals;
• and
• C1-C6 halogenoalkyl radicals, and
• R2 represents an aryl group that is a phenyl, an aralkyl group that is a benzyl or phenethyl, or a cycloalkyl group, wherein said aryl group or said aralkyl group is optionally substituted with at least one group chosen from halogen atoms,
• wherein R1 and R2 do not each simultaneously represent a phenyl group.