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US 11,906,674 B2Granted
Sealable, mesoporous silica shell nanoreactor
AssigneeThe Regents of the University of California
InventorTing Guo
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Abstract
The present technology relates to nanomaterials and methods of their use, and more specifically to methods and structures using nanomaterials to fiducially measure radiation dosing.
Claims20
A method of measuring radiation dosage, the method comprising:
- incorporating a probing molecule within a nanoreactor;
- irradiating the nanoreactor with irradiation energy for a period of time sufficient for the probing molecule to react with hydroxyl radicals to form a fluorescent molecule;
- and
- measuring a dosage of irradiation based on the fluorescent molecules formed, wherein the dosage measurements are substantially linearly responsive within a dose range.
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A method of producing a nanoreactor configured to measure irradiation dosage, the method comprising:
- incorporating probing molecules within a hollow mesoporous nanoreactor;
- and
- mixing a water-soluble polymer with the hollow mesoporous nanoreactor subsequent sufficient time for probing molecules to be contained within the hollow mesoporous nanoreactor, wherein the water-soluble polymer is configured to substantially seal pores of the hollow mesoporous nanoreactor.
A nanoreactor comprising:
- a hollow mesoporous shell;
- an aqueous solution contained within the hollow mesoporous shell, wherein the aqueous solution comprises a plurality of probing molecules;
- and
- an external coating on the hollow mesoporous shell comprising a polymeric material.
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Dependencies are inferred from the claim text.