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US 11,906,536 B2Granted
Lung cancer detection kit or device, and detection method
AssigneesToray Industries, Inc., National Cancer Center
InventorsHiroko Sudo, Hitoshi Nobumasa, Satoko Kozono, Satoshi Kondou, Junpei Kawauchi, Atsushi Ochiai, Motohiro Kojima
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Abstract
It is intended to provide a kit or a device for the detection of lung cancer and a method for detecting lung cancer. The present invention provides a kit or a device for the detection of lung cancer, comprising a nucleic acid capable of specifically binding to a miRNA in a sample from a subject, and a method for detecting lung cancer, comprising measuring the miRNA in vitro.
Claims6
A method for detecting lung cancer in a human subject, comprising
- measuring an expression level of hsa-miR-3162-5p in a blood, serum or plasma sample from the subject;
- comparing the measured expression level of hsa-miR-3162-5p to a control expression level for a healthy subject;
- detecting an increased level of hsa-miR-3162-5p in the sample from the subject as compared to the control expression level from the sample from the healthy subject;
- wherein the increased level of hsa-miR-3162-5p indicates that the subject has lung cancer;
- and
- wherein the method further comprises treating the subject for the lung cancer or performing a diagnostic procedure on the subject with the lung cancer:
- wherein the treatment comprises surgery, radiotherapy, chemotherapy or a combination thereof;
- and
- wherein the diagnostic procedure comprises chest X-ray examination or diagnostic imaging of the lung of the human subject.
6 more elements
Dependencies are inferred from the claim text.