US 11,906,533 B2Granted

Chemical sensing system

AssigneeStratuscent Inc.

InventorsMojtaba Khomami Abadi, Amir Bahador Gahroosi, Matthew V. Gould, Ashok Prabhu Masilamani

Life of this patent

Estimating the term…

Loading patent…

Abstract

A chemical sensing system is described. The chemical sensing system can include a plurality of sensors arranged on at least one substrate. The sensors may have differing sensitivities to sense different analytes, and may each be configured to output a signal in response to sensing one or more of the different analytes. The chemical sensing system can further include a computer processor programmed to receive the signals output from the plurality of sensors. The computer processor may be further programmed to determine a concentration of analytes in the sample based, at least in part, on the received signals and a model relating the signals or information derived from the signals to an output representation having bases corresponding to analytes.

Claims20

Dependent claims

A chemical sensing system, comprising:

a plurality of sensors arranged on at least one substrate, wherein a first sensor and a second sensor of the plurality of sensors have different sensitivities to sense at least one analyte in a sample, each of the plurality of sensors being configured to output a signal in response to sensing the at least one analyte;
and
a computer processor programmed to:
receive the signals output from the plurality of sensors;
and
determine a concentration of the at least one analyte in the sample based, at least in part, on the received signals and a model trained to relate the signals or information derived from the signals to an output representation having bases corresponding to analytes, the analytes including the at least one analyte, wherein the concentration is a scalar value in conjunction with a particular unit of measurement,
wherein the model comprises:
a first model relating the signals output from the plurality of sensors to a feature representation;
and
a second model relating the feature representation to the output representation, the second model comprising:
a first sub-model relating a latent representation to a straightened orthogonal representation, wherein:
one-dimensional manifolds in the straightened orthogonal representation corresponding to varying concentrations of a same analyte have zero angle between them;
and
one-dimensional manifolds in the straightened orthogonal representation corresponding to different analytes are orthogonal.

11 more elements

A chemical sensing system, comprising:

a plurality of sensors arranged on at least one substrate, wherein a first sensor and a second sensor of the plurality of sensors have different sensitivities to sense at least one analyte in a sample, each of the plurality of sensors being configured to output a signal in response to sensing the at least one analyte;
and
a computer processor programmed to:
receive the signals output from the plurality of sensors;
and
determine a concentration of the at least one analyte in the sample based, at least in part, on the received signals and a model trained to relate the signals or information derived from the signals to an output representation having bases corresponding to analytes, the analytes including the at least one analyte, wherein the concentration is a scalar value in conjunction with a particular unit of measurement,
wherein the model comprises:
a first model relating the signals output from the plurality of sensors to a feature representation;
and
a second model relating the feature representation to the output representation, the second model comprising:
a first sub-model relating a straightened orthogonal representation to the output representation, wherein the sub-model:
relates the straightened orthogonal representation to a non-linearized output representation having standard bases associated with the analytes;
and
relates the non-linearized output representation to the output representation;
and
wherein a change in a location of a point in the output representation corresponding to an analyte concentration in the sample is a linear function of a change in the analyte concentration in the sample.

13 more elements

Dependencies are inferred from the claim text.

Facts

Application: 16/456,244Filed 28 Jun 2019 · continuation
Priority: 29 Jan 2018
Published: US 2019/0234973 A117 Oct 2019
Granted: 20 Feb 2024
Term ends: Not estimatedThe source records don’t support an estimate.

Classification19 codes

G01N 35/00722
Control arrangements for automatic analysers: communications; Identification
G06N 3/088
Learning methods: non-supervised learning, e.g. competitive learning
B82Y 15/00
Nanotechnology for interacting, sensing or actuating
G01N 33/0031
Concerning the detector: comprising two or more sensors, e.g. a sensor array

Family

Application62/623,440Us provisional application · filed 29 Jan 2018
Application16/261,195Parent of this continuation · filed 29 Jan 2019
US 2019/0317118 A1Pre-grant publication · published 17 Oct 2019
US 10,386,379 B1Parent of this continuation
US 2019/0234973 A1Published application
US 11,906,533 B2This patent

From the US filing history. Foreign family members aren’t listed.

Timeline

Citations

Open elsewhere

Building an agent or pulling many patents? Use the API or MCP server instead of scraping pages. Get an API key