US 11,906,517 B2 · Method for diagnostics, treatment and prevention of Parkinson's disease

Abstract

The present invention relates to the field of medicine and in particular to Parkinson's disease (PD). Specifically the present invention relates to methods and means for early detection of PD. The invention relates also to methods and means for treatment or prophylaxis of PD. In the method of the invention a probability of a subject developing or having Parkinson's disease (PD) is determined by measuring the relative abundances of one or multiple microbial taxa in a sample from a subject; and the probability of the subject developing or having PD is determined based on the measured abundances. The present invention provides a novel approach for the diagnostics of PD.

Claims15

Dependent claims

A method for treatment or prevention of Parkinson's disease (PD) in an individual, comprising administering to said individual a composition that increases the abundance of Prevotellaceae in the intestine, wherein active ingredients of the composition consist of Prevotellaceae.

Dependencies are inferred from the claim text.

Facts

Application

17/933,952Filed 21 Sep 2022 · continuation

Priority

FI 2014549228 May 2014

Published

US 2023/0221314 A113 Jul 2023

Granted

20 Feb 2024

Term ends

Not estimatedThe source records don’t support an estimate.

Classification13 codes

G01N 33/56911
For microorganisms, e.g. protozoa, bacteria, viruses: bacteria
A61K 35/741
Bacteria: probiotics
A61P 25/16
For treating abnormal movements, e.g. chorea, dyskinesia: anti-Parkinson drugs
C12Q 1/04
Involving viable microorganisms: determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides;…

Family

PCT/FI2015/050374Parent of this division · filed 28 May 2015

Application16/186,663Parent of this division · filed 12 Nov 2018

US 10,139,408 B2Parent of this division · filed 27 Nov 2018

Application17/116,045Parent of this continuation · filed 9 Dec 2020

US 2023/0221314 A1Pre-grant publication · published 13 Jul 2023

US 11,499,971 B2Parent of this continuation

Application17/116,045Parent of this division

Application15/314,240Parent of this division

US 2017/0191998 A1Published application

US 2019/0137493 A1Published application

US 2021/0109098 A1Published application

US 11,906,517 B2This patent

From the US filing history. Foreign family members aren’t listed.

Method for diagnostics, treatment and prevention of Parkinson's disease

Life of this patent

Method for diagnostics, treatment and prevention of Parkinson's disease

Life of this patent

Abstract

Claims15