Methods and systems for preparing cytological samples
AssigneeLeavitt Medical, Inc.
InventorSorin Musat
Life of this patent
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Abstract
The disclosed methods for preparing cytological samples may include placing a cytological sample in a concave filter in a filtration system, applying a negative pressure to an outer side of the concave filter with a vacuum device to withdraw a liquid from the cytological sample, applying a sectionable matrix material over the filtered cellular material within the concave filter, and removing an assembly including the filtered cellular material and the sectionable matrix material from the filtration system. Various other related methods, systems, and materials are also disclosed.
Claims21
A system for preparing cytological samples, the system comprising:
- a filter cavity shaped and sized for receiving a concave filter and a cytological sample within a cavity of the concave filter;
- and
- a vacuum device in fluid communication with the filter cavity, the vacuum device configured to apply a negative pressure to an outer surface of the concave filter to withdraw a liquid from the cytological sample, wherein, after applying the negative pressure to the outer surface of the concave filter, a sectional matrix material comprising a liquid or molten sectional matrix material is applied over a filtered cellular material positioned within the concave filter.
A sectionable matrix material for processing cytological samples, comprising:
- a first sectionable matrix material, comprising:
- a bottom surface;
- a central depression on a side of the first sectionable matrix material opposite the bottom surface, wherein the central depression is shaped and sized to receive a concave filter;
- and
- a plurality of channels extending through the first sectionable matrix material from an inner surface of the central depression to the bottom surface, wherein the channels are configured to apply a negative pressure across the first sectionable matrix material;
- and
- a second sectional matrix material comprising a liquid or molten sectional matrix material, wherein the second sectional matrix material is applied over a filtered cellular material positioned within the concave filter after applying the negative pressure across the first sectionable matrix material.
A system for preparing cytological samples, the system comprising:
- a filter cavity shaped and sized for receiving a concave filter and a cytological sample within a cavity of the concave filter;
- and
- a vacuum device in fluid communication with the filter cavity, the vacuum device configured to apply a negative pressure to an outer surface of the concave filter to withdraw a liquid from the cytological sample, wherein:
- prior to applying a sectionable matrix material, an additional concave filter is positioned over a filtered cellular material;
- and
- the filtered cellular material is positioned within the concave filter.
Dependencies are inferred from the claim text.