Anti-Jagged1 antigen binding proteins
AssigneeAmgen Inc.
InventorsBrian D. Bennett, Chadwick T. King, Jonathan Phillips
Life of this patent
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Abstract
Methods of treating conditions related to lung disease using an antigen binding protein specific for the Jagged1 polypeptide are provided.
Claims13
A method of treating a subject with a condition related to lung disease, wherein the lung disease is a disease of the airways, the method comprising administering to the subject a therapeutically effective amount of an antigen binding protein that specifically binds to a human Jagged1 polypeptide, wherein the antigen binding protein is an antibody or a fragment thereof, and wherein the antibody comprises a CDRL1, a CDRL2, a CDRL3, a CDRH1, a CDRH2, and a CDRH3, wherein CDRL1 comprises SEQ ID NO:
- 98, CDRL2 comprises SEQ ID NO:
- 99, CDRL3 comprises SEQ ID NO:
- 100, CDRH1 comprises SEQ ID NO:
- 230, CDRH2 comprises SEQ ID NO:
- 231, and CDRH3 comprises SEQ ID NO:
- 232.
Dependencies are inferred from the claim text.