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AssigneesBlackthorn Therapeutics, Inc., The Scripps Research Institute
InventorsEdward Roberts, Miguel A. Guerrero, Mariangela Urbano, Hugh Rosen, Robert M. Jones, Candace Mae Laxamana, Xianrui Zhao, Eric Douglas Turtle
Estimating the term…
Compounds are provided that antagonize the kappa-opioid receptor (KOR) and products containing such compounds, as well as to methods of their use and synthesis. Such compounds have the structure of Formula (I), or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope or salt thereof: wherein X, Y, R1, R2, R4, R5, R6, R7, R8 and R11 are as defined herein.
A pharmaceutical composition comprising a compound having the following structure, or a pharmaceutically acceptable hydrate, solvate, isotope or salt thereof, together with at least one pharmaceutically acceptable carrier, diluent or excipient:
Dependencies are inferred from the claim text.