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US 11,897,870 B2Granted
5-hydroxytryptamine receptor 7 activity modulators and their method of use
AssigneeTemple University of the Commonwealth System of Higher Education
InventorsDaniel J. Canney, Benjamin E. Blass, Rong Gao, Magid Abou-Gharbia
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Abstract
Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity.
Claims7
A compound according to the following formula,
- or a pharmaceutically acceptable salt thereof, wherein
- n is 2;
- each of R1a and R1b is C1-6 linear alkyl;
- and
- R3 is optionally substituted heteroaryl.
2 more elements
Dependencies are inferred from the claim text.