Biomimetic electrically conductive hyaluronic acid-based hydrogels
AssigneeThe Regents of the University of California
InventorRebecca Bierman
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Abstract
An electrically conductive hyaluronic acid-based hydrogel is disclosed that is a crosslinked porous scaffold having a graphene-based material encapsulated or in contact within the porous scaffold. The graphene-based material includes one or more of graphene oxide foam, reduced graphene oxide foam, nanoplatelets, nanoparticles, or fibers. The porous scaffold may be formed over an implanted bioelectronic device such as a microelectrode array having a plurality of electrodes. The porous scaffold may also be used to control the differentiation of cells including Neural Stem/Progenitor Cells (NS/PCs).
Claims7
An implantable bioelectronic device comprising a plurality of electrodes, the device comprising a polymer coated body and a plurality of metallic electrodes, wherein an electrically conductive hyaluronic acid-based hydrogel crosslinked into a porous scaffold is adhered to the polymer coated body and wherein the crosslinked porous scaffold is punctuated with holes or apertures located adjacent to the plurality of metallic electrodes, wherein the holes or apertures contain a graphene-based material therein.
Dependencies are inferred from the claim text.