Ultrahigh ductility, novel Mg—Li based alloys for biomedical applications
AssigneeUniversity of Pittsburgh—Of the Commonwealth System of Higher Education
InventorsPrashant N. Kumta, Jingyao Wu, Oleg Velikokhatnyi
Life of this patent
Estimating the term…
Abstract
The invention includes compositions including magnesium-lithium alloys containing various alloying elements for medical implant devices. The devices are constructed of the compositions or have applied thereto a coating formed therefrom. Within the structure of the magnesium-lithium alloy, there is a co-existence of alpha and beta phases. The invention also includes methods of preparing the magnesium-lithium alloys and articles, such as medical implant devices, for use in medical applications, including orthopedic, dental, craniofacial and cardiovascular surgery.
Claims7
A method for preparing a medical implant device, comprising:
- fabricating a substrate structured for implanting into a body, comprising:
- forming an alloy, comprising:
- I melting 9.00% by weight of lithium, 0.96% by weight of zinc, and 0.01% by weight of aluminum, and a remainder of magnesium based on the total weight of the alloy, or
- II melting about 8.99% by weight of lithium, 0.87% by weight of zinc, 1.07% by weight of aluminum, and a remainder of magnesium based on the total weight of the alloy, or
- III melting about 6.11% by weight of lithium, 0.92% by weight of zinc, 0.04% by weight of aluminum, and a remainder of magnesium based on the total weight of the alloy,
- wherein the alloy of I, II, or III is structured to exhibit a co-existence of alpha and beta phases,
- wherein the alloy of I, II, or III exhibits one or more of improved ductility and elasticity;
- casting the alloy of I, II, or III to form a casted alloy;
- and
- extruding the casted alloy to form the substrate in an extruded form.
A method for preparing a medical implant device, comprising:
- fabricating a substrate structured for implanting into a body, comprising:
- forming an alloy, comprising:
- melting from about 5% by weight to about 11% by weight of lithium and a remainder of magnesium based on the total weight of the alloy, comprising:
- high energy mechanical alloying of the lithium and the magnesium;
- followed by uniaxial or isostatic compaction;
- and
- followed by sintering,
- wherein the alloy is structured to exhibit a co-existence of alpha and beta phases, and
- wherein the alloy exhibits one or more of improved ductility and elasticity;
- casting the alloy to form a casted alloy;
- and
- extruding the casted alloy to form the substrate in an extruded form.
Dependencies are inferred from the claim text.