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AssigneeMie University
InventorsAkira Mizoguchi, Koji Tanaka, Kazushi Kimura, Tetsuya Nosaka, Kyosuke Tanaka, Shujie Wang, Aika Kaito, Kousyoku Sai, Yuji Toiyama, Hidemasa Goto, Masahiko Sugimoto, Yuuhei Nishimura
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Provided is a vital stain inspection method for distinguishing between cancer cells and normal cells within a lumen, or on the serous membrane side of an organ, by means of laser irradiation after organ tissue has been stained by curcumin, Red #3 or Red #106, which are edible color dyes.
A method for detecting cancer progression comprising staining an organ tissue suspected of having cancer with curcumin and then laser irradiating the organ tissue from serosal side or lumen using a multiphoton laser microscopic endoscope, confocal laser microscopic endoscope or laser fluorescent microscopic endoscope, and visualizing Meissner's plexus or Auerbach's plexus present in the organ tissue, wherein the organ tissue is digestive tract tissue, and a primary lesion is in mucosal epithelium.
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