Method for preventing pregnancy
AssigneeEstetra Srl
InventorsMaud Jost, Glwadys Rausin
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Abstract
The present invention relates to a method for the management of dysmenorrhea involving administration of an estrogenic component which is preferably selected from the group consisting of estetrol and estetrol-like compounds. Estetrol-like compounds have been surprisingly found to be capable of mitigating dysmenorrhea, either when used alone or in combination with progestogenic components, and this to an extent surpassing the effect obtained with other compositions and with a favourable side-effect profile compared to currently available methods.
Claims20
A method for preventing pregnancy, comprising orally administering to a female subject a composition comprising from 15 to 25 mg estetrol and from 1 to 4 mg drospirenone, wherein administration of said composition does not result in a hemostatic change exceeding a boundary of a normal hemostatic range.
A method for preventing pregnancy, comprising orally administering to a female subject a composition comprising from 15 to 25 mg estetrol and from 1 to 4 mg drospirenone, wherein administration of said composition does not result in an increased risk of developing venous thromboembolism (VTE) in the subject.
A method for preventing pregnancy, comprising orally administering to a female subject a composition comprising from 15 to 25 mg estetrol and from 1 to 4 mg drospirenone, wherein the subject's risk of developing VTE associated with administration of said composition is lower as compared to the risk associated with administration of other combined oral contraceptives.
A method of contraception that avoids hemostatic changes exceeding a boundary of a normal hemostatic range in a subject, comprising administering to the subject a combined oral contraceptive (COC) comprising from 15 to 25 mg estetrol and from 1 to 4 mg drospirenone.
A method of contraception that avoids hemostatic changes exceeding a boundary of a normal hemostatic range in a subject, comprising administering to the subject a combined oral contraceptive (COC) comprising from 15 to 25 mg estetrol and from 1 to 4 mg drospirenone, wherein administration of said COC does not increase the subject's risk of developing VTE.
Dependencies are inferred from the claim text.